Republicans are headed for a blowout election win that seems certain to seize more than enough seats to knock out the Democrats and take control of the House.

The Hill 2010 Midterm Election poll, surveying nearly 17,000 likely voters in 42 toss-up districts over four weeks, points to a massive Republican wave that, barring an extraordinary turnaround, will deliver crushing nationwide defeats for President Obama’s party.

The data suggest a GOP pickup that could easily top 50 seats (the party needs 39 for control of the House).

Of the 42 districts polled for The Hill, all but two of which are currently Democratic, 31 had Republicans in the lead. Democrats were up in just seven, and four were tied. In addition, there are some 15 Democratic districts that are so far into the GOP win column that they weren’t polled. That would suggest at least 46 GOP pickups, plus whatever the party gets out of another 40 or 50 seats that some experts believe are in play.

“We didn’t even poll in about 15 districts that are already too far gone for Democrats,” said Mark Penn, whose firm, Penn Schoen Berland, conducted the poll. “So that, along with our entire series of polls, points to something in the range of a 50-seat gain for Republicans.”

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